Acute Tubular Necrosis

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چکیده

A rapid rise in creatinine following periods of hypotension is most commonly due to acute tubular necrosis. In ATN, urinalysis usually shows granular casts. Urine sodium is typically high due to tubular sodium loss, concentration is typically above 30 mmol/l. The urine to plasma osmolality ratio <1:1, the ability to concentrate urine is preserved despite sodium loss. Acute Tubular Necrosis is associated with accelerated hypertension, hypotension, diabetes, liver failure, eclampsia, aminoglycosides, Cephalosporins, Cisplatin, Amphotericin and Ciclosporin.

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تاریخ انتشار 2006